Eric Marsh

Eric Marsh, MD, PhD


Eric Marsh is an Attending Physician, Professor of Neurology and Clinical Director of the Neurogenetics Program at the Children’s Hospital of Philadelphia. He is also an Associate Professor of Neurology and Pediatrics at the Perelman School of Medicine, University of Pennsylvania, and the Clinical Director of the Orphan Disease Center at UPenn.

Dr. Marsh’s research program focuses on identifying the genetic, cellular, and network mechanisms of seizures, autism, and cognitive dysfunction in children. His team combines molecular and neurophysiological tools in mouse models to ask questions about the interaction of normal development with single gene mutations to determine how the brain responds to perturbations in development.

His group also takes a translational approach to determine the network and electrophysiological alterations in the brains of children with intractable, early-onset epilepsies. intracranial and scalp EEG from children with intractable focal epilepsies. They extract specific features from the EEG, primarily interictal spikes and sharps, to determine whether they inform about network dynamics or can act as a biomarker for seizure onset or post-surgery prognosis.

Marsh received a BS in biology from Haverford College, an MS and PhD in physiology and neuroscience from New York University, and an MD from the New York School of Medicine.