Alex Felix, PhD

Research Interests

Gene therapy, oligonucleotides, RNA metabolism, neuro disorders, organoids

Education

BS, Biotechnology, Rovira i Virgili University
MS, Pharmaceutical Industry and Biotechnology, Pompeu Fabra University
PhD, Biomedicine, University of Barcelona

Hometown

Tarragona, Spain

Hobbies

Hiking, movies, rap music, video games

Alexey Bogush, PhD

Research Interests

Current: cfDNA and TLR9/ROS signal transduction pathway.
Former: Viruses as a delivery vectors; molecular mechanisms leading to impaired motor neurons physiology in ALS.

Education

BS, MS, Biochemistry, Virology, Moscow State University
PhD, Genetics, Russian Academy of Medical Sciences

Hometown

Moscow, Russia

Hobbies

Russian theatre and theatre history in the early 20th century (Vsevolod Meyerhold); interior design ideas, decoration and organization for home.

Jennine Dawicki-McKenna, PhD

Research Interests

chromatin and protein-DNA interactions, epigenetics, transcriptional regulation and RNA processing

Education

PhD, Cell and Molecular Biology, University of Pennsylvania Perelman School of Medicine

Hometown

Penndel, PA

Hobbies

Learning new things, trying to spread my enthusiasm of coding to others, bioinformatics

Benjamin Prosser, PhD

Benjamin (Ben) Prosser is an Associate Professor of Physiology at the University of Pennsylvania Perelman School of Medicine. He earned his Ph.D. in Molecular Medicine under Dr. Martin Schneider at the University of Maryland School of Medicine in 2009, and then completed his post-doc in Molecular Cardiology under Dr. Jon Lederer at Maryland in 2013. Dr. Prosser started his own group at the University of Pennsylvania in 2014 with a focus on the heart and was named the Outstanding Early Career Investigator by the American Heart Association in 2017. In 2020, he became Associate Director of the historic Pennsylvania Muscle Institute as well as lead coordinator of a Leducq Trans-Atlantic Network of Excellence – an international consortium investigating the role of the cytoskeleton in heart failure. In 2021, Dr. Prosser was named a fellow of the International Society of Heart Research (ISHR) and received the Outstanding Investigator Award at the ISHR World Congress in 2022.

In 2018, Dr. Prosser’s daughter Lucy was born and diagnosed with STXBP1 encephalopathy, a rare, genetic neurodevelopmental disorder. Dr. Prosser started a separate research arm in his lab focused on developing new therapies for STXBP1 and related disorders. This work ultimately spurred the formation of the Center for Epilepsy and Neurodevelopmental Disorders (ENDD), which Dr. Prosser directs with his colleagues Drs. Beverly Davidson and Ingo Helbig of the Children’s Hospital of Philadelphia (CHOP). ENDD represents a cross-institute, interdisciplinary collaboration of fundamental, translational, and clinical researchers focused on developing genetic therapies for STXBP1, SYNGAP1, and related neurodevelopmental disorders.

Lab Members

Alexey Bogush, PhD

Research Specialist

Jennine Dawicki-McKenna, PhD

Senior Research Investigator

Alex Felix, PhD

Postdoctoral fellow

Nick Marotta, BS

PhD Student

Nanthana Ravichandran, BS

Research Specialist

Taryn Wilson, BS

Research Specialist